Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-199a
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
Hif1Ī±
Cancer name
Ovarian Cancer
Cancer site
Ovary
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Down
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MiR-199a modulates cisplatin resistance in ovarian cancer by targeting Hif1Ī±.
Tissue resource
ovarian cancer tissue samples and corresponding normal tissues
ovarian cancer cisplatin-resistant cell lines C13*
ovarian cancer cisplatin-sensitive cell lines OV2008
Experiment
qRT-PCR,Western blot
Institute
the First Affiliated Hospital of Harbin Medical University
Ottawa Regional Cancer Center
Country
China
Canada
Continent
Asia
North American
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.