hsa-miR-410-3p

ncRNA information

ncRNA name

hsa-miR-410-3p

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

HMGB1

Cancer information

Cancer name

Pancreatic Ductal Adenocarcinoma

Cancer site

Pancreas

Treatment information

Treatment type

Chemotherapy

Drug

Gemcitabine

Impact of wild-type ncRNA on chemotherapy resistance

Down

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MicroRNA-410-3p attenuates gemcitabine resistance in pancreatic ductal adenocarcinoma by inhibiting HMGB1-mediated autophagy.

Tissue resource

pancreatic ductal adenocarcinoma tumor tissues

human pancreatic ductal adenocarcinoma cell lines MiaPaCa2

human pancreatic ductal adenocarcinoma cell lines PANC-1

Experiment

qRT-PCR


Institute

the West China Hospital of Sichuan University

Shanghai Cell Bank

Country

China

Continent

Asia