hsa-miR-770

ncRNA information

ncRNA name

hsa-miR-770

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Diagnosis

Upstream regulatory factors

Not available

Downstream target

STMN1

Cancer information

Cancer name

Triple-Negative Breast Cancer

Cancer site

Breast

Treatment information

Treatment type

Chemotherapy

Drug

Doxorubicin

Impact of wild-type ncRNA on chemotherapy resistance

Down

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Our results proved that miR-770 could suppress the doxorubicin-resistance and metastasis of TNBC cells.

Tissue resource

breast tissues

triple-negative breast cancer cell lines MDA-MB-231

triple-negative breast cancer cell lines MDA-MB-468

Experiment

qRT-PCR,Western blot,Dual-luciferase reporter assay


Institute

Shandong University

American Type Culture Collection

Country

China

USA

Continent

Asia

North American