Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-647
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
ANK2
Cancer name
Gastric Cancer
Cancer site
Stomach
Treatment type
Chemotherapy
Drug
Vincristine
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Down
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
16
Male patients
10
Female patients
6
Age range and number
Not available
PMID
Description
Overexpression of miR-647 was also demonstrated to sensitize tumors to chemotherapy in vivo.
Tissue resource
pairs of gastric cancer tissues and adjacent nontumor tissues
gastric cancer vincristine-resistant cell lines SGC7901/VCR
gastric cancer cell lines GES-1
Experiment
qRT-PCR,Western blot
Institute
the First Affiliated Hospital of Guangxi Medical University
the Cell Center of Xiangya Medical University
the Cell Center of Xiangya Medical University
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.