hsa-miR-647

ncRNA information

ncRNA name

hsa-miR-647

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

ANK2

Cancer information

Cancer name

Gastric Cancer

Cancer site

Stomach

Treatment information

Treatment type

Chemotherapy

Drug

Vincristine

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Down

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

16

Male patients

10

Female patients

6

Age range and number

Not available

Research information

PMID

Description

Overexpression of miR-647 was also demonstrated to sensitize tumors to chemotherapy in vivo.

Tissue resource

pairs of gastric cancer tissues and adjacent nontumor tissues

gastric cancer vincristine-resistant cell lines SGC7901/VCR

gastric cancer cell lines GES-1

Experiment

qRT-PCR,Western blot


Institute

the First Affiliated Hospital of Guangxi Medical University

the Cell Center of Xiangya Medical University

the Cell Center of Xiangya Medical University

Country

China

Continent

Asia