Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
NEAT1
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-193b-3p/CCND1
Cancer name
Cervical Cancer
Cancer site
Cervix Uteri
Treatment type
Radiotherapy
Impact of wild-type ncRNA on radiotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
72
Male patients
37
Female patients
35
Age range and number
Not available
PMID
Description
NEAT1 could facilitate the radio-resistance of cervical cancer via competitively binding miR-193b-3p to up-regulate the expression of cyclin D1.
Tissue resource
pairs of brand-new CC tissue samples and matched normal tissue samples
human cervical cancer cell lines HeLa
human cervical cancer cell lines SiHa
Experiment
qRT-PCR,Western blot,Luciferase reporter assay
Institute
China-Japan Union Hospital of Jilin University
American Type Culture Collection
Country
China
USA
Continent
Asia
North American
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.