Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
CCDC26
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
c-KIT
Cancer name
Gastrointestinal Stromal Tumor
Cancer site
Stomach, Small Intestine
Treatment type
Chemotherapy
Drug
Imatinib
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Up
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
We found that human GIST-882 cells with lower CCDC26 expressio were less sensitive to imatinib compared with GIST-T1 cells with higher CCDC26 expression.
Tissue resource
human gastrointestinal stromal tumors cell lines GIST-882
human gastrointestinal stromal tumors cell lines GISTT1
Experiment
qRT-PCR,Western blot
Institute
the Chinese Academy of Science Cell Bank
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.