CTRR-ncRNA

ncRNA information

ncRNA name

hsa-miR-21

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Esophageal Squamous Cell Carcinoma

Cancer site

Esophagus

Treatment information

Treatment type

Radiotherapy

Impact of wild-type ncRNA on radiotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Up

Number of patients

63

Male patients

34

Female patients

29

Age range and number

18(<60)+45(>=60)

Research information

PMID

29568234

Description

Downregulation of microRNA-21 inhibited radiation-resistance of esophageal squamous cell carcinoma.

Tissue resource

paired esophageal squamous cell carcinoma tissues and adjacent nontumoral tissues

human esophageal squamous cell carcinoma cell lines TE-1

human esophageal squamous cell carcinoma cell lines EC1

human esophageal squamous cell carcinoma cell lines KYSE140

Experiment

qRT-PCR,Western blot

Institute

Sichuan Cancer Hospital

the Chinese Academy of Sciences

Country

China

Continent

Asia