Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
DANCR
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
Yes
Biomarker application
Treatment
Upstream regulatory factors
Not available
Downstream target
AXL/PI3K/Akt/NF-ĪŗB signaling pathway
Cancer name
Glioma
Cancer site
Brain, Central Nervous System
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Down
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
We found that DANCR expression was negatively correlated with cisplatin sensitivity in glioma cells.
Tissue resource
human glioma cell lines U87MG
human glioma cell lines U251MG
human glioma cell lines LN18
human glioma cell lines U138MG
Experiment
qRT-PCR,Western blot,Luciferase reporter assay
Institute
Chinese Academy of Sciences Cell Bank
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.