Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-30a-5p
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
Yes
Biomarker application
Treatment
Upstream regulatory factors
Not available
Downstream target
IGF1R
Cancer name
Melanoma
Cancer site
Skin
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Transfection of miR-30a-5p mimic or inhibitor could alter the sensitivity of melanoma cells to cisplatin.
Tissue resource
human melanoma cancer cell lines M8
human melanoma cancer cisplatin-resistant cell lines M8/DDP
human melanoma cancer cell lines SK-Mel-19
human melanoma cancer cisplatin-resistant cell lines SK-Mel-19/DDP
human embryonic kidney cell lines HEK-293T
Experiment
qRT-PCR,Western blot,Dual-luciferase reporter assay
Institute
Jennio Biotech
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.