Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
PCBP1-AS1
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
AR/AR-V7
Cancer name
Prostate Cancer
Cancer site
None
Treatment type
Chemotherapy
Drug
Enzalutamide
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
LncRNA PCBP1-AS1-mediated AR/AR-V7 deubiquitination enhances prostate cancer enzalutamide resistance
Tissue resource
tumor tissue from BPH patients and HSPC patients and 12 CRPC patients
prostate cancer cell lines LNCaP
prostate cancer cell lines C4-2
Experiment
None
Institute
the Affiliated Cancer Hospital of Zhengzhou University
Tianjin Medical University Second Hospital
Country
China
China
Continent
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.