hsa-miR-21

ncRNA information

ncRNA name

hsa-miR-21

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

HBP1

Cancer information

Cancer name

Lung Adenocarcinoma

Cancer site

Lung

Treatment information

Treatment type

Chemotherapy

Drug

Paclitaxel

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MiR-21 improves invasion and migration of drug-resistant lung adenocarcinoma cancer cell.

Tissue resource

human lung cancer cell line A549

Experiment

qRT-PCR,Western blot,Dual-luciferase reporter assay


Institute

BeNa Culture Collection

Country

China

Continent

Asia