Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
CILA1
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
Yes
Biomarker application
Treatment
Upstream regulatory factors
Not available
Downstream target
Wnt/Ī²-catenin signaling pathway
Cancer name
Tongue Squamous Cell Carcinoma
Cancer site
Tongue
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Up
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
155
Male patients
94
Female patients
61
Age range and number
42(<50)+113(>=50)
PMID
Description
Upregulation of CILA1 promotes EMT, invasiveness, and chemo-resistance in TSCC cells.
Tissue resource
tongue squamous cell carcinoma specimens tissues
tongue squamous cell carcinoma cell lines CAL27
tongue squamous cell carcinoma cell lines SCC9
Experiment
qRT-PCR,Western blot
Institute
Sun Yat-sen Memorial Hospital/the West China Hospital/the Affiliated Hospital of North Sichuan Medical College
American Type Culture Collection
Country
China
USA
Continent
Asia
North American
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.