hsa-miR-505

ncRNA information

ncRNA name

hsa-miR-505

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

RASSF8

Cancer information

Cancer name

Colorectal Cancer

Cancer site

Colon, Rectum, and Anus

Treatment information

Treatment type

Chemotherapy

Drug

Methotrexate

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MiR-505 expression significantly increased in resistant tissues compared with sensitive tissues.

Tissue resource

colorectal cancer tissue specimens

colorectal cancer cell lines SW480

colorectal cancer cell lines SW620

colorectal cancer cell lines LS174T

Experiment

qRT-PCR,Western blot,Dual-luciferase reporter assay


Institute

the Fifth People's Hospital of Ji'nan

BeNa Culture Collection

Country

China

Continent

Asia