Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
LINC00894-002
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
TGF-Ī² signaling pathway
Cancer name
Breast Cancer
Cancer site
Breast
Treatment type
Chemotherapy
Drug
Tamoxifen
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Up
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Downregulation of LINC00894-002 Contributes to Tamoxifen Resistance by Enhancing the TGF-b Signaling Pathway.
Tissue resource
breast cancer cell lines MCF-7/WT
breast cancer tamoxifen-resistant cell lines MCF-7/TamR
Experiment
qRT-PCR,Western blot
Institute
Country
Continent
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.