Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa_circ_0001313
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
HGF/c-Met
Downstream target
Not available
Cancer name
Non-Small Cell Lung Cancer
Cancer site
Lung
Treatment type
Chemotherapy
Drug
Gefitinib/Erlotinib
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
372
Male patients
292
Female patients
80
Age range and number
Not available
PMID
Description
HGF/c-Met regulates expression of SAE2 and cirRNA CCDC66 to increase EMT and drug resistance of LADC cells.
Tissue resource
non-small cell lung cancer tissue specimens
non-small cell lung cancer cell lines H125
non-small cell lung cancer cell lines H23
non-small cell lung cancer cell lines H226
non-small cell lung cancer cell lines H838
non-small cell lung cancer cell lines H1437
non-small cell lung cancer cell lines H2009
non-small cell lung cancer cell lines H2087
non-small cell lung cancer cell lines A549
Experiment
qRT-PCR
Institute
National Chung Hsing University
American Type Culture Collection
Country
China
USA
Continent
Asia
North American
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.