hsa-miR-1268a

ncRNA information

ncRNA name

hsa-miR-1268a

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

ABCC1

Cancer information

Cancer name

Glioblastoma

Cancer site

Brain, Central Nervous System

Treatment information

Treatment type

Chemotherapy

Drug

Temozolomide

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Down

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Our data indicated that miR-1268a enhanced TMZ sensitivity in GBM cells.

Tissue resource

samples of primary glioblastom and samples from recurrent glioblastom

glioblastom cell lines U87

glioblastom cell lines LN229

Experiment

qRT-PCR,Western blot,Dual-luciferase reporter assay


Institute

the Nanfang hospital

American Type Culture Collection

Country

China

USA

Continent

Asia

North American