Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
HOXD-AS1
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-130a-3p/ZEB1
Cancer name
Cervical Cancer
Cancer site
Cervix Uteri
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
HOXD-AS1 enhanced chemoresistance of cisplatin-resistant CC cells through modulating miR-130a-3p/ZEB1.
Tissue resource
cervical cancer tissues and non-malignant tissues
cervical cancer cell lines CaSki
cervical cancer cell lines HeLa
Experiment
qRT-PCR,Western blot,Dual-luciferase reporter assay
Institute
the First Affiliated Hospital of Soochow University
the Tumor Cell Bank of the Chinese Academy of Medical Science
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.