Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-27b-3p
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
PPARĪ³
Cancer name
Anaplastic Thyroid Cancer
Cancer site
Thyroid
Treatment type
Chemotherapy
Drug
Doxorubicin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Down
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Targeted inhibition of miR-27b can increase the sensitivity of SW1736/Dox and 8305C/Dox cells.
Tissue resource
human anaplastic thyroid carcinoma cell lines SW1736
human anaplastic thyroid carcinoma cell lines 8305C
Experiment
qRT-PCR,Western blot,Dual-luciferase reporter assay
Institute
the Shanghai Institute of Cell Biology, Chinese Academy of Sciences
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.