FTH1P3

ncRNA information

ncRNA name

FTH1P3

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-206/ABCB1

Cancer information

Cancer name

Breast Cancer

Cancer site

Breast

Treatment information

Treatment type

Chemotherapy

Drug

Paclitaxel

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Long noncoding RNA FTH1P3 activates paclitaxel resistance in breast cancer through miR-206/ABCB1.

Tissue resource

paclitaxel-resistant and paclitaxel-sensitive breast cancer tissue

human breast cancer cell lines MCF-7

human breast cancer cell lines MDA-MB-231

human breast cancer cell lines MDA-MB-468

human breast cancer cell lines MDA-MB-453

normal human breast epithelial cell lines MCF-10A

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

the First Affiliated Hospital of Zhengzhou University and the First People's Hospital of Shangqiu

American Type Culture Collection

Country

China

USA

Continent

Asia

North American