Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
FTH1P3
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-206/ABCB1
Cancer name
Breast Cancer
Cancer site
Breast
Treatment type
Chemotherapy
Drug
Paclitaxel
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Long noncoding RNA FTH1P3 activates paclitaxel resistance in breast cancer through miR-206/ABCB1.
Tissue resource
paclitaxel-resistant and paclitaxel-sensitive breast cancer tissue
human breast cancer cell lines MCF-7
human breast cancer cell lines MDA-MB-231
human breast cancer cell lines MDA-MB-468
human breast cancer cell lines MDA-MB-453
normal human breast epithelial cell lines MCF-10A
Experiment
qRT-PCR,Western blot,Luciferase reporter assay
Institute
the First Affiliated Hospital of Zhengzhou University and the First People's Hospital of Shangqiu
American Type Culture Collection
Country
China
USA
Continent
Asia
North American
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.