Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa_circ_0007874
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
Yes
Biomarker application
Upstream regulatory factors
Not available
Downstream target
TRAF4/Eg5
Cancer name
Breast Cancer
Cancer site
Breast
Treatment type
Chemotherapy
Drug
Monastrol
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Circular RNA-MTO1 suppresses breast cancer cell viability and reverses monastrol resistance through regulating the TRAF4/Eg5.
Tissue resource
human breast cancer cell lines MDA-MB-231
human breast cancer cell lines MCF-7
human breast cancer cell lines MDA-MB-453
human breast cancer cell lines SKBR-3
human breast cancer cell lines T47D
human breast cancer cell lines MDA-MB-468
Experiment
qRT-PCR,Western blot
Institute
Chinese Academy of Sciences
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.