Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
EBIC
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Treatment
Upstream regulatory factors
Not available
Downstream target
Wnt/Ī²-catenin signaling pathway
Cancer name
Ovarian Cancer
Cancer site
Ovary
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
We found that overexpression of lncRNA EBIC could promote the proliferation, invasion and migration and improved cells cisplatin resistance by Wnt/Ī²-catenin signaling pathway in ovarian cancer.
Tissue resource
ovarian cancer tissues
human ovarian cancer cell lines OVCA429
human ovarian cancer cell lines SKOV-3
normal human ovarian epithelial cell lines HOSE
Experiment
qRT-PCR,Western blot
Institute
West China Second Hospital, Sichuan University
the Shanghai Institute of Biochemistry and Cell Biology
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.