EBIC

ncRNA information

ncRNA name

EBIC

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

No

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

Wnt/Ī²-catenin signaling pathway

Cancer information

Cancer name

Ovarian Cancer

Cancer site

Ovary

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

We found that overexpression of lncRNA EBIC could promote the proliferation, invasion and migration and improved cells cisplatin resistance by Wnt/Ī²-catenin signaling pathway in ovarian cancer.

Tissue resource

ovarian cancer tissues

human ovarian cancer cell lines OVCA429

human ovarian cancer cell lines SKOV-3

normal human ovarian epithelial cell lines HOSE

Experiment

qRT-PCR,Western blot


Institute

West China Second Hospital, Sichuan University

the Shanghai Institute of Biochemistry and Cell Biology

Country

China

Continent

Asia