MALAT1

ncRNA information

ncRNA name

MALAT1

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Cervical Carcinoma

Cancer site

Cervix Uteri

Treatment information

Treatment type

Radiotherapy

Impact of wild-type ncRNA on radiotherapy resistance

Up

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

In cervical carcinoma, MALAT1 can interact with miR-143 to modulate tumor cell survival, apoptosis and cell cycle, thus affecting radiotherapy efficiency.

Tissue resource

cervical cancer tissues

human cervical cancer cell lines CaSki

Experiment

qRT-PCR


Institute

Jinan Maternal and Child Health Hospital

Cell Bank, Shanghai Institute of Cell Biology, Chinese Academy of Science

Country

China

Continent

Asia