Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-143-3p
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
CIAPIN1
Cancer name
Triple-Negative Breast Cancer
Cancer site
Breast
Treatment type
Chemotherapy
Drug
Paclitaxel
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Down
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Hsa-miRNA-143-3p as a tumor suppressive microRNA may be a novel target to effectively reverse MDR of TNBC in vivo.
Tissue resource
human embryonic kidney cell lines HEK-293T
triple-negative breast cancer cell lines BT-20
triple-negative breast cancer cell lines MDA-MB-231
triple-negative breast cancer cell lines MCF7
triple-negative breast cancer cell lines SKBr-3
triple-negative breast cancer cell lines Lovo
triple-negative breast cancer cell lines epG2A549
triple-negative breast cancer cell lines MRC-5
Experiment
qRT-PCR,Western blot
Institute
the Shanghai Institute of Biochemistry and Cell Biology
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.