Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
NEAT1
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
Yes
Biomarker application
Treatment
Upstream regulatory factors
Not available
Downstream target
miR-214-3p
Cancer name
Urothelial Carcinoma of Bladder
Cancer site
Bladder
Treatment type
Chemotherapy
Drug
Doxorubicin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
NEAT1 contributed to DOX resistance of UBC through the Wnt/Ī²-catenin pathway partly by negatively regulating miR-214-3p expression.
Tissue resource
urothelial bladder cancerand matched normal urothelial bladder tissues
human urothelial bladder cancer cell lines J82
human urothelial bladder cancer cell lines T24
Experiment
qRT-PCR,Western blot
Institute
Shengjing Hospital
the Chinese Academy of Sciences
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.