Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
EGFR-AS1
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
Yes
Biomarker application
Prognosis
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Non-Small Cell Lung Cancer
Cancer site
Lung
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Up
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Overexpression of lncRNA EGFR-AS1 is associated with a poor prognosis and promotes chemotherapy resistance in non-small cell lung cancer.
Tissue resource
serum, tumor tissues and corresponding adjacent normal tissues
human non-small cell lung cancer cell lines A549
human non-small cell lung cancer cell lines NCI-H460
human non-small cell lung cancer cell lines NCI-H1299
human non-small cell lung cancer cell lines NCI-H358
human non-small cell lung cancer cell lines HCC827
human non-small cell lung cancer cell lines NCI-H292
human non-small cell lung cancer cell lines NCI-H838
Experiment
qRT-PCR,Western blot,Luciferase reporter assay
Institute
Jiangxi Chest Hospital and the First Affiliated Hospital of Nanchang University
American Type Culture Collection
the Chinese Academy of Sciences
Country
China
USA
China
Continent
Asia
North American
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.