hsa-miR-193a-3p

ncRNA information

ncRNA name

hsa-miR-193a-3p

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

SRSF2

Cancer information

Cancer name

Gastric Cancer

Cancer site

Stomach

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Up

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

30485589

Description

We found that an elevated level of miR-193a-3p triggered the development of cisplatin resistance in CD44(+) cells.

Tissue resource

gastric cancer cell lines MKN45

gastric cancer cell lines AGS

gastric cancer cell lines KATO III

Experiment

RT-PCR,Western blot,Luciferase reporter assay

Institute

Country

Continent

Institutes for Systems Genetics, West China Hospital
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