Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa_circ_0004015
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-1183/PDPK1 signaling pathway
Cancer name
Non-Small Cell Lung Cancer
Cancer site
Lung
Treatment type
Chemotherapy
Drug
Gefitinib
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
circ_0016760/miR-1183/PDPK1 signaling pathway might play vital roles in the tumorigenesis of NSCLC
Tissue resource
non-small cell lung cancer and corresponding normal tissues
human lung adenocarcinoma cell lines A549
human lung adenocarcinoma cell lines H1975
human lung adenocarcinoma cell lines H358
human lung adenocarcinoma cell lines H1299
human lung adenocarcinoma cell lines HCC827
human airway epithelial cell lines 16HBE
Experiment
qRT-PCR,Luciferase reporter assay
Institute
the Third Affiliated Hospital of Soochow University
the type Culture Collection of Chinese Academy of Sciences
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.