Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
LINC01118
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-134/ABCC1
Cancer name
Ovarian Cancer
Cancer site
Ovary
Treatment type
Chemotherapy
Drug
Paclitaxel
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Up
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
LINC01118 acted as an oncogene and modulated EOC paclitaxel sensitivity by regulating miR-134/ABCC1.
Tissue resource
ovarian cancer tissues
human epithelial ovarian carcinoma cell lines SKOV3-TR30
human epithelial ovarian carcinoma cell lines SKOV3
human epithelial ovarian carcinoma cell lines A2780
human epithelial ovarian carcinoma cell lines COC1
Experiment
RT-PCR,Western blot,Luciferase reporter assay
Institute
the Department of Gynecology of Shengjing Hospital of China Medical University
Women's Hospital, School of Medicine, Zhejiang University
the Tumor Cell Band Research Institute of the Chinese Academy of Medical Science
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.