Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
ANCR
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
PTEN
Cancer name
Nasopharyngeal Carcinoma
Cancer site
Nasopharynx
Treatment type
Radiotherapy
Impact of wild-type ncRNA on radiotherapy resistance
Up
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
30
Male patients
17
Female patients
13
Age range and number
7(<60)+23(>=60)
PMID
Description
ANCR expression is upregulated in NPC and promotes NPC growth and radiation resistance through an epigenetic regulation of PTEN expression.
Tissue resource
nasopharyngeal carcinoma tissues and corresponding normal tissues
human nasopharyngeal carcinoma cell lines CNE1
human nasopharyngeal carcinoma cell lines CNE2
human nasopharyngeal carcinoma cell lines SUNE1
human nasopharyngeal carcinoma cell line C666-1
human nasopharyngeal carcinoma cell line HONE1
human nasopharyngeal carcinoma cell line HNE1
human normal nasopharyngeal epithelial cell lines NP-69
Experiment
qRT-PCR,Western blot
Institute
Zhangjiagang First People's Hospital
Shanghai Institutes for Biological Sciences Cell Resource Center
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.