Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-338-5p
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
FERMT2
Cancer name
Esophageal Squamous Cancer
Cancer site
Esophagus
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Down
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MiR-338-5p reduced cell proliferation, colony formation, migration, and cisplatin resistance in an ESCC cell line CE-81T.
Tissue resource
esophageal squamous cell carcinoma cell lines KYSE-30
esophageal squamous cell carcinoma cell lines KYSE-70
esophageal squamous cell carcinoma cell lines KYSE-270
esophageal squamous cell carcinoma cell lines OE-21
esophageal squamous cell carcinoma cell lines CE-81T
Experiment
qRT-PCR,Western blot,Microarray analysis,Luciferase reporter assay
Institute
Country
Continent
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.