Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-29c
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
ITGB1
Cancer name
Nasopharyngeal Cancer
Cancer site
Nasopharynx
Treatment type
Chemotherapy
Drug
Paclitaxel
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Down
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MiR-29c regulates resistance to Taxol in NPC by targeting ITGB1. Our research indicates that miR-29c may have potential use in Taxol-resistant NPC therapy.
Tissue resource
nasopharyngeal cancer cell lines SUNE-1
nasopharyngeal cancer cell lines C666-1
Experiment
qRT-PCR,Western blot,Dual-luciferase reporter assay
Institute
the cell bank of Chinese Academy of Sciences
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.