Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-483-3p
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
FAM171B
Cancer name
Colorectal Cancer
Cancer site
Colon, Rectum, and Anus
Treatment type
Chemotherapy
Drug
Oxaliplatin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Down
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
FAM171B is a functional target of miR-483-3p in the regulation of oxaliplatin resistance in human CRC cells.
Tissue resource
human colorectal cancer oxaliplatin-resistant cell lines HCT116/L
human colorectal cancer cell lines HCT116
human colorectal cancer cell lines LOVO
human colorectal cancer cell lines SW480
Experiment
qRT-PCR
Institute
the cell bank of the Chinese Academy of Sciences
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.