Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-574-3p
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
ZEB1
Cancer name
Gastric Carcinoma
Cancer site
Stomach
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Down
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MiR-574-3p inhibited the EMT and enhanced cisplatin sensitivity in GC cells by suppressing ZEB1.
Tissue resource
human embryonic kidney cell lines HEK-293T
human gastric cancer cell lines SGC7901
human gastric cancer cell lines AGS
human gastric cancer cell lines BGC823
human gastric cancer cell lines MGC803
human gastric cancer cell lines HGC27
Experiment
qRT-PCR,Dual-luciferase reporter assay
Institute
the Institute of Biochemistry and Cell Biology
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.