DLEU1

ncRNA information

ncRNA name

DLEU1

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

Yes

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-99b/HS3ST3B1

Cancer information

Cancer name

Bladder Cancer

Cancer site

Bladder

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Our study revealed a novel role for the DLEU1/miR-99b/HS3ST3B1 in regulating proliferation, invasion, and cisplatin resistance of BCA cells.

Tissue resource

bladder cancer and adjacent normal tissues

human bladder cancer cell lines T24

human bladder cancer cell lines SW780

primary normal human bladder epithelial cell lines

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

the Fourth Affiliated Hospital of China Medical University

the Shanghai Institute of Cell Biology

American Type Culture Collection

Country

China

USA

Continent

Asia

North American