Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
RMRP
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
ZNRF3
Cancer name
Glioma
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
Temozolomide
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Down
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
lncRNA-RMRP/ZNRF3 axis and Wnt/Ī²-catenin signaling regulates the progression and temozolomide resistance in glioma
Tissue resource
glioma tissues and age-matched patients with relapsed glioma after TMZ-based chemotherapy
glioma cell lines U251
Experiment
None
Institute
Beijing Tiantan Hospital of Capital Medical University
the Cell Bank of the Chinese Academy of Sciences
Country
China
China
Continent
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.