Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
CASC11
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Ovarian Squamous Cell Carcinoma
Cancer site
Ovary
Treatment type
Chemotherapy
Drug
Carboplatin/Cisplatin/Oxaliplatin/Tetraplatin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Overexpression of CASC11 led to increased cancer cell viability under oxaliplatin, tetraplatin, cisplatin, and carboplatin treatment, while CASC11 siRNA silencing played an opposite role.
Tissue resource
blood from oral squamous cell carcinoma patients and healthy volunteers
human ovarian carcinoma cell lines UWB1.289
Experiment
qRT-PCR
Institute
the First Affiliated Hospital of Soochow University
American Type Culture Collection
Country
China
USA
Continent
Asia
North American
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.