CASC11

ncRNA information

ncRNA name

CASC11

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Ovarian Squamous Cell Carcinoma

Cancer site

Ovary

Treatment information

Treatment type

Chemotherapy

Drug

Carboplatin/Cisplatin/Oxaliplatin/Tetraplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Up

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Overexpression of CASC11 led to increased cancer cell viability under oxaliplatin, tetraplatin, cisplatin, and carboplatin treatment, while CASC11 siRNA silencing played an opposite role.

Tissue resource

blood from oral squamous cell carcinoma patients and healthy volunteers

human ovarian carcinoma cell lines UWB1.289

Experiment

qRT-PCR


Institute

the First Affiliated Hospital of Soochow University

American Type Culture Collection

Country

China

USA

Continent

Asia

North American