CTRR-ncRNA

ncRNA information

ncRNA name

hsa-miR-130b

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

PTEN

Cancer information

Cancer name

Renal Cell Carcinoma

Cancer site

Kindey

Treatment information

Treatment type

Chemotherapy

Drug

Sunitinib

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

32

Male patients

25

Female patients

7

Age range and number

Not available

Research information

PMID

31195398

Description

Knockdown of miR-130b improved sunitinib resistance in Caki-1-SR cells.

Tissue resource

renal cell carcinoma tissue samples

Experiment

qRT-PCR,Western blot

Institute

Hiroshima University

Country

Japan

Continent

Asia