hsa-miR-15b

ncRNA information

ncRNA name

hsa-miR-15b

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Renal Cell Carcinoma

Cancer site

Kidney

Treatment information

Treatment type

Chemotherapy

Drug

Sunitinib

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Up

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Overexpression of miR-15b Promotes Resistance to Sunitinib in Renal Cell Carcinoma.

Tissue resource

renal cell carcinoma cell lines 786-O

renal cell carcinoma cell lines 769-P

renal cell carcinoma cell lines A498

renal cell carcinoma cell lines ACHN

renal cell carcinoma cell lines Caki-1

renal cell carcinoma cell lines Caki-2

renal cell carcinoma cell lines OS-RC-2

Experiment

qRT-PCR,Western blot


Institute

National Infrastructure of Cell Line Resource

Country

China

Continent

Asia