Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-15b
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Renal Cell Carcinoma
Cancer site
Kidney
Treatment type
Chemotherapy
Drug
Sunitinib
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Up
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Overexpression of miR-15b Promotes Resistance to Sunitinib in Renal Cell Carcinoma.
Tissue resource
renal cell carcinoma cell lines 786-O
renal cell carcinoma cell lines 769-P
renal cell carcinoma cell lines A498
renal cell carcinoma cell lines ACHN
renal cell carcinoma cell lines Caki-1
renal cell carcinoma cell lines Caki-2
renal cell carcinoma cell lines OS-RC-2
Experiment
qRT-PCR,Western blot
Institute
National Infrastructure of Cell Line Resource
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.