Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
TUG1
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Nrf2
Downstream target
Not available
Cancer name
Urothelial Carcinoma of Bladder
Cancer site
Bladder
Treatment type
Chemotherapy
Drug
Adriamycin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Down
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Nrf2 induces the up-regulation of TUG1 to promote progression and ADMresistance in UCB.
Tissue resource
urothelial carcinoma of bladder tissues and paired normal tissues
human urothelial carcinoma of bladder cell lines EJ-1
human urothelial carcinoma of bladder cell lines 5637
human urothelial carcinoma of bladder cell lines T24
normal human urothelial cell lines SV-HUC-1
Experiment
qRT-PCR,Western blot
Institute
Huaihe Hospital of Henan University
American Type Culture Collection
Country
China
USA
Continent
Asia
North American
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.