Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
Lnc-DC
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
STAT3/cytokine
Cancer name
Breast Cancer
Cancer site
qRT-PCR,Western blot
Treatment type
Chemotherapy
Drug
Tamoxifen
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Lnc-DC promotes estrogen independent growth and tamoxifen resistance in breast cancer
Tissue resource
breast cancer cell lines MCF-7
breast cancer cell lines T47D
embryonic kidney cell lines 293T
Experiment
None
Institute
American Type Culture Collection
Country
United States
Continent
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.