CRNDE

ncRNA information

ncRNA name

CRNDE

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-33a/HMGA2

Cancer information

Cancer name

Liver Cancer

Cancer site

Liver

Treatment information

Treatment type

Chemotherapy

Drug

Adriamycin

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Down

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Downregulated CRNDE and upregulated miR-33a-inhibited cells drug-resistance and promoted their apoptosis in liver cancer drug-resistant cells.

Tissue resource

liver cancer cell lines HepG2

liver cancer cell lines BEL-7402

Experiment

qRT-PCR,Western blot,Dual-Luciferase reporter assay


Institute

Shanghai Cell Bank, Chinese Academy of Sciences

Country

China

Continent

Asia