Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
SNHG20
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-140-5p/NDRG3
Cancer name
Gastric Cancer
Cancer site
Stomach
Treatment type
Chemotherapy
Drug
5-Fluorouracil
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
The SNHG20/miR-140-5p/NDRG3 may be involved in mediating resistance to 5-FU in gastric cancer.
Tissue resource
gastric cancer cell lines BGC-823
gastric cancer cell lines AGS
Experiment
qRT-PCR,Western blot,Luciferase reporter assay
Institute
Wuhan Fine Biotech Co., Ltd
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.