SNHG20

ncRNA information

ncRNA name

SNHG20

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-140-5p/NDRG3

Cancer information

Cancer name

Gastric Cancer

Cancer site

Stomach

Treatment information

Treatment type

Chemotherapy

Drug

5-Fluorouracil

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Up

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

The SNHG20/miR-140-5p/NDRG3 may be involved in mediating resistance to 5-FU in gastric cancer.

Tissue resource

gastric cancer cell lines BGC-823

gastric cancer cell lines AGS

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

Wuhan Fine Biotech Co., Ltd

Country

China

Continent

Asia