CTRR-ncRNA

ncRNA information

ncRNA name

HULC

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

No

Biomarker application

Upstream regulatory factors

METase

Downstream target

FoxM1

Cancer information

Cancer name

Gastric Cancer

Cancer site

Stomach

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Down

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

31485766

Description

METase suppressed autophagy to reduce CDDP resistance of drug-resistant gastric cancer cells through regulating HULC/FoxM1 pathway.

Tissue resource

human gastric cancer cell lines SGC7901

human gastric cancer cell lines MGC-803

Experiment

qRT-PCR,Western blot

Institute

Cell Bank of Chinese Academy of Sciences

Country

China

Continent

Asia