SNHG7

ncRNA information

ncRNA name

SNHG7

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

PI3K/Akt

Cancer information

Cancer name

Non-Small Cell Lung Cancer

Cancer site

Lung

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Up

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

SNHG7 induces the development of cisplatin-resistance in NSCLC through upregulating MRD1 and BCRP via PI3K/AKT pathway.

Tissue resource

tumor and para-cancerous tissues

non-small cell lung cancer cisplatin-resistant cell lines A549/DDP

Experiment

qRT-PCR,Western blot


Institute

Xinjiang Uygur Autonomous Region People's Hospital

American Type Culture Collection

Country

China

USA

Continent

Asia

North American