GSTM3TV2

ncRNA information

ncRNA name

GSTM3TV2

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

let-7/LAT2/OLR1

Cancer information

Cancer name

Pancreatic Cancer

Cancer site

Pancreas

Treatment information

Treatment type

Chemotherapy

Drug

Gemcitabine

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Up

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Further studies demonstrated that GSTM3TV2, overexpressed in gemcitabine-resistant cells, enhanced the gemcitabine resistance of pancreatic cancer cells in vitro and in vivo.

Tissue resource

pancreatic adenocarcinoma patient tissue samples

pancreatic ductal adenocarcinoma cell lines AsPC-1

pancreatic ductal adenocarcinoma cell lines MIAPaCa-2

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

Peking Union Medical College Hospital

Heidelberg University

Country

China

Germany

Continent

Asia

Europe