Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
SNHG22
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-2467/Gal-1
Cancer name
Epithelial Ovarian Carcinoma
Cancer site
Ovary
Treatment type
Chemotherapy
Drug
Cisplatin/Paclitaxel
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Down
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Knockdown of SNHG22 expression increased the sensitivity of EOC cells to cisplatin and paclitaxel.
Tissue resource
human normal ovarian and epithelial ovarian cancer tissues
epithelial ovarian carcinoma cell lines Hey
epithelial ovarian carcinoma cell lines OAW28
epithelial ovarian carcinoma cell lines COV-362
epithelial ovarian carcinoma cell lines OVCAR-3
epithelial ovarian carcinoma cell lines CAOV3
epithelial ovarian carcinoma cell lines SKOV3
epithelial ovarian carcinoma cell lines A2780
epithelial ovarian carcinoma cisplatin-resistant cell lines A2780/CP
Experiment
qRT-PCR,Luciferase reporter assay
Institute
Obstetrics & Gynecology Hospital of Fudan University
the Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.