SNHG22

ncRNA information

ncRNA name

SNHG22

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-2467/Gal-1

Cancer information

Cancer name

Epithelial Ovarian Carcinoma

Cancer site

Ovary

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin/Paclitaxel

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Down

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Up

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Knockdown of SNHG22 expression increased the sensitivity of EOC cells to cisplatin and paclitaxel.

Tissue resource

human normal ovarian and epithelial ovarian cancer tissues

epithelial ovarian carcinoma cell lines Hey

epithelial ovarian carcinoma cell lines OAW28

epithelial ovarian carcinoma cell lines COV-362

epithelial ovarian carcinoma cell lines OVCAR-3

epithelial ovarian carcinoma cell lines CAOV3

epithelial ovarian carcinoma cell lines SKOV3

epithelial ovarian carcinoma cell lines A2780

epithelial ovarian carcinoma cisplatin-resistant cell lines A2780/CP

Experiment

qRT-PCR,Luciferase reporter assay


Institute

Obstetrics & Gynecology Hospital of Fudan University

the Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences

Country

China

Continent

Asia