Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
HCP5
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-214-3p/HDGF
Cancer name
Pancreatic Cancer
Cancer site
Pancreas
Treatment type
Chemotherapy
Drug
Gemcitabine
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Targeting lncRNA HCP5 may improve gemcitabine-based therapeutic efficacy.
Tissue resource
pancreatic cancer tissue samples and matched normal tissue
pancreatic cancer cell lines PANC-1
pancreatic cancer cell lines SW 1990
Experiment
qRT-PCR,Western blot,Dual-Luciferase reporter assay
Institute
Third Xiangya Hospital
the Cell Collection Committee of the Chinese Academy of Sciences
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.