HCP5

ncRNA information

ncRNA name

HCP5

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-214-3p/HDGF

Cancer information

Cancer name

Pancreatic Cancer

Cancer site

Pancreas

Treatment information

Treatment type

Chemotherapy

Drug

Gemcitabine

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Up

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Targeting lncRNA HCP5 may improve gemcitabine-based therapeutic efficacy.

Tissue resource

pancreatic cancer tissue samples and matched normal tissue

pancreatic cancer cell lines PANC-1

pancreatic cancer cell lines SW 1990

Experiment

qRT-PCR,Western blot,Dual-Luciferase reporter assay


Institute

Third Xiangya Hospital

the Cell Collection Committee of the Chinese Academy of Sciences

Country

China

Continent

Asia