ADAMTS9-AS2

ncRNA information

ncRNA name

ADAMTS9-AS2

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

FUS/MDM2

Cancer information

Cancer name

Glioblastoma

Cancer site

Brain, Central Nervous System

Treatment information

Treatment type

Chemotherapy

Drug

Temozolomide

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

The ADAMTS9-AS2/FUS/MDM2 may represent a suitable prognostic biomarker and a potential target in TMZ-resistant GBM therapy.

Tissue resource

glioma tissues

human glioma cell lines T98G

human glioma cell lines U118

Experiment

qRT-PCR,Western blot


Institute

Xiangya Hospital of Central South University

the Cancer Research Institute, Central South University

Country

China

Continent

Asia