Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-409-5p
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
NUP43
Cancer name
Chronic Myeloid Leukemia
Cancer site
Leukemia
Treatment type
Chemotherapy
Drug
Imatinib
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Up
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MiRNA-409-5p overexpression enhances Imatinib resistance in CML.
Tissue resource
peripheral blood of acute myeloid leukemia patients
human chronic myeloid leukemia cell lines K562
human chronic myeloid leukemia cell lines KG-1a
Experiment
qRT-PCR,Western blot,Dual-Luciferase reporter assay
Institute
the First People's Hospital of Hefei City
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.