hsa-miR-409-5p

ncRNA information

ncRNA name

hsa-miR-409-5p

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

NUP43

Cancer information

Cancer name

Chronic Myeloid Leukemia

Cancer site

Leukemia

Treatment information

Treatment type

Chemotherapy

Drug

Imatinib

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Up

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MiRNA-409-5p overexpression enhances Imatinib resistance in CML.

Tissue resource

peripheral blood of acute myeloid leukemia patients

human chronic myeloid leukemia cell lines K562

human chronic myeloid leukemia cell lines KG-1a

Experiment

qRT-PCR,Western blot,Dual-Luciferase reporter assay


Institute

the First People's Hospital of Hefei City

Country

China

Continent

Asia