hsa-miR-182-5p

ncRNA information

ncRNA name

hsa-miR-182-5p

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

GLI2

Cancer information

Cancer name

Lung Adenocarcinoma

Cancer site

Lung

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Down

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

The miR-182-5p/GLI2 modulates tumorigenesis and cisplatin-resistance in LADC cells, by influencing the HHSP.

Tissue resource

lung cancer tissue samples

human parental lung adenocarcinoma cell lines NCI-H460

human parental lung adenocarcinoma cell lines A549

lung adenocarcinoma cisplatin-resistant cell lines CisR

Experiment

qRT-PCR,Luciferase reporter assay


Institute

Medical University of Graz

Trinity College

Country

Austria

Ireland

Continent

Europe